Lanthanum-Doped Bismuth Phosphate: Engineering a Next-Generation Antimicrobial Material

Abstract

Chemical influence of the implant surface creates the bactericidal feature to avoid different infections associated with dental implants. Regardless of the successful use of bismuth against dermal and mucosal infections, the antibacterial efficacy of bismuth is still under consideration. The inhibition zone of fungal pathogens caused by varying BiPO₄ nanoparticle concentrations on culture media is measured, as well as by inhibiting spore germination, the antifungal activity was demonstrated. BiPO₄ nanoparticles were found to have strong antifungal activity against some fungal pathogen examined in this investigation. This study looks into the antifungal and antibacterial properties of bismuth phosphate doped with lanthanum applying the disc diffusion approach to E. Gram-positive S. aureus and gram-negative E.coli. In this study, lanthanum doped bismuth phosphate has been synthesized through sol gel method. Prepared nanoparticles are characterized by Ultraviolet- visible spectroscopy (UV-Vis) and Fourier transform infrared spectroscopy (FTIR). The very low cut off wavelengths and band gap for La³⁺ doped BiPO₄ crystals are roughly 290 nm and 0.68 eV respectively based on the UV-Visible spectra. By confirming the existence of functional groups, FTIR results demonstrated that the synthesis of lanthanum-doped bismuth phosphate nanomaterials was successful. Higher antibacterial activity against both S. aureus and E. coli.  has been demonstrated by the lanthanum-doped bismuth phosphate nanoparticles.